Publications from the GLASS Consortium

  1. Glioma through the looking GLASS: molecular evolution of diffuse gliomas and the Glioma Longitudinal Analysis Consortium. Neuro-Oncology, 2018. DOI:10.1093/neuonc/noy020
  2. Longitudinal molecular trajectories of diffuse glioma patients. Nature 2019. DOI: 10.1038/s41586-019-1775-1
  3. iGLASS: imaging integration into the Glioma Longitudinal Analysis Consortium. Neuro-Oncology, 2020. DOI:10.1093/neuonc/noaa160
  4. Longitudinal analysis of diffuse glioma reveals cell state dynamics at recurrence associated with changes in genetics and the microenvironment. Biorxiv 2021. DOI:

Commentary on the 2020 Nature paper: The Magnifying GLASS: Longitudinal Analysis of Adult Diffuse Gliomas. Ashwin Narayanan, Sevin Turcan. Cell, 2020. DOI:10.1016/j.cell.2020.01.016.

A non-exhaustive list of publications in which GLASS data were used:

  1. Alghamri et al. Tumor mutational burden predicts survival in patients with low-grade gliomas expressing mutated IDH1. Neurooncol Adv. 2020 Mar 27;2(1):vdaa042. doi:10.1093/noajnl/vdaa042.
  2. Anderson et al. Molecular and clonal evolution in recurrent metastatic gliosarcoma. Cold Spring Harb Mol Case Stud. 2020 Feb 3;6(1):a004671. doi: 10.1101/mcs.a004671.
  3. Gromeier et al. Very low mutation burden is a feature of inflamed recurrent glioblastomas responsive to cancer immunotherapy. Nat Commun. 2021 Jan 13;12(1):352. doi:10.1038/s41467-020-20469-6.
  4. Kumthekar et al. A first-in-human phase 0 clinical study of RNA interference-based spherical nucleic acids in patients with recurrent glioblastoma. Sci Transl Med. 2021 Mar 10;13(584):eabb3945. doi:10.1126/scitranslmed.abb3945.
  5. Garofano et al. Pathway-based classification of glioblastoma uncovers a mitochondrial subtype with therapeutic vulnerabilities. Nat Cancer. 2021 Feb;2(2):141-156. doi:10.1038/s43018-020-00159-4.
  6. Kocakavuk et al. Radiotherapy is associated with a deletion signature that contributes to poor outcomes in patients with cancer. Nat Genetics. 2021 Feb;2(2):141-156. doi:10.1038/s41588-021-00874-3.
  7. Claus et al. Environmental and sex-specific molecular signatures of glioma causation. Neuro Oncol. 2021 May 4;noab103. 10.1093/neuonc/noab103.
  8. Wu et al. Metabolic expression profiling stratifies diffuse lower-grade glioma into three distinct tumour subtypes. Br J Cancer. 2021 Jul;125(2):255-264.doi: 10.1038/s41416-021-01418-6.